基本情況
劉君羊，男，中共黨員。五邑大學藥學與食品工程學院副教授，碩士研究生導師。
聯系方式
地址：廣東省江門市蓬江區東成村22號五邑大學藥學與食品工程學院
郵編：529020
郵箱：liujy@wyu.edu.cn
電話：-
工作經歷
2022.02至今 ，五邑大學，藥學與食品工程學院，副教授，碩士生導師；
2017.12至2022.02，南方科技大學，高級研究學者、研究助理教授/研究副教授；2012.10至2017.11，北京大學、香港理工大學、南方科技大學，博士后/訪學；
教育及學習經歷
2006.09-2012.01 北京大學 博士
2001.09-2005.07 南昌大學 本科
主要研究方向
活性藥物、天然產物的合成及結構修飾
科研項目
1. 國家自然科學基金，面上項目，2024.01-2027.12，主持；
2. 國家自然科學基金，青年基金項目，2017.01-2019.12，主持；
3. 廣東省教育廳重點建設學科科研能力提升項目，2022.1-2024.12，主持；
4. 國家重點實驗室，開放課題項目，2023.1-2024.12，主持；
5. 深圳市科創委，面上項目，2020.06-2023.6，主持；
發表學術論文
1. Liu, Junyang; Wu, Jianlei; Fan, Jian-Hong; Yan, Xin; Mei, Guangjian; Li, Chuang-Chuang, Asymmetric Total Synthesis of Cyclocitrinol. J. Am. Chem. Soc. 2018, 140, (16), 5365-5369.
2. Liu, Xin#; Liu, Junyang#; Wu, Jianlei; Huang, Guocheng; Liang, Rong; Chung, Lung Wa; Li, Chuang-Chuang*, Asymmetric Total Synthesis of Cerorubenic Acid-III. J. Am. Chem. Soc. 2019, 141, (7), 2872-2877.
3. Liu, Junyang#; Liu, Xin#; Wu, Jianlei; Li, Chuang-Chuang*, Total Synthesis of Natural Products Containing a Bridgehead Double Bond. Chem 2020, 6, (3), 579-615.
4. Gu, Chen-Chen; Long, Xiong-En; Chen, Xiuping; Liu, Junyang*; Li, Chuang-Chuang*, Recent Natural Product Total Syntheses Involving Cycloadditions of Allenes. Chin. J. Chem. 2025, 43, online.
5. Nan, Huiru; Long, Xiong-En; He, Jianfei; Xing, Hailiang; Cheng, Min-Jing; Peng, Jin-Bao; Ye, Tao*; Yan, Jia-Lei*; Liu, Junyang*, Total Synthesis of the Marine Cyclic Depsipeptide Lagunamide D. Mar. Drugs 2025, 23, (3), 99.
6. Liu, Haoyang; Xing, Hailiang; Yu, Peilan; Wang, Yanjie; Yan, Jia-Lei; Liu, Junyang*; Wang, Min*, Base-Controlled Synthesis of Heteroatom-Embedded 9-Membered Cycloalkynes and 6-Membered Sultams through Copper-Catalyzed Cyclization. J. Org. Chem. 2025, 90, (2), 984-993.
7. Wang, Chenqi; Liu, Junyang*; Ye, Tao*, Synergy of prediction rule and total synthesis in solving the stereochemical puzzle of eucalactam B. Org. Chem. Front. 2025, 12, (1), 70-75.
8. Liu, Junyang; Chen, Kai; Guo, Yian; Chen, Ying; Ye, Tao*, Total Synthesis of Rhizopodin Enabled by a Late-Stage Oxazole Ring Formation Strategy. Org. Lett. 2024, 26, (41), 8928-8933.
9. Yan, Jia-Lei; Nan, Huiru; Fang, Xiaoyu; Long, Xiong-En; Jiang, Yu; Liu, Junyang*, The isolation, bioactivity, and synthesis of natural products from Litsea verticillate with anti-HIV activities. Front. Pharmacol. 2024, 15, 1477878.
10. Xiao, Yi#; Liu, Junyang#; Jiang, Yangyang; Guo, Yian; Ye, Tao*, Total Syntheses and Stereochemical Assignment of Acremolides A and B. Molecules 2024, 29, (15), 3599.
11. Hou, Bao-Long*; Liu, Junyang*; Qiao, Chuang*; Li, Chuang-Chuang*, Total synthesis of natural products containing bicyclo[n.2.2] ring systems. Tetrahedron Lett. 2024, 135, 154871.
12. He, Yujie; Chen, Jintao; Jiang, Yu; Fang, Xiaoyu; Liu, Junyang*; Yan, Jia-Lei*, N-Heterocyclic Carbene Catalyzed Reactions Involving Acetylenic Breslow and/or Acylazolium as Key Intermediates. Chem. Rec. 2024, 24, (12), e202400165.
13. Liu, Junyang#; Tang, Shoubin#; Yan, Jia-Lei; Ye, Tao*, Design and Synthesis of Novel Helix Mimetics Based on the Covalent H-Bond Replacement and Amide Surrogate. Molecules 2023, 28, (2), 780.
14. Liu, Junyang; Chen, Hang; Wang, Min; He, Wangjin; Yan, Jia-Lei*, Organocatalytic asymmetric synthesis of P-stereogenic molecules. Front. Chem. 2023, 11.
15. Hui, Chunngai#,*; Wang, Zhuo#; Xie, Yusheng*; Liu, Junyang*, Contemporary synthesis of bioactive cyclobutane natural products. Green Synth. Catal. 2023, 4, (1), 1-6.
16. Liu, Junyang*; Chen, Ying; Luesch, Hendrik; Ye, Tao*, Total Synthesis of des-Thiomethyllooekeyolide A. Org. Lett. 2022, 24, (40), 7260-7264.
17. Wu, Jianlei#; Liu, Junyang#, *; Fan, Jian-Hong; Xie, Zhi-Dong; Qin, Hukun; Li, Chuang-Chuang*, Evolution of Routes for Asymmetric Total Synthesis of Cyclocitrinol Enabled by Type II [5+2] Cycloaddition?. Chin. J. Chem. 2021, 39, (5), 1247-1254.
18. Liu, Xin#; Liu, Junyang#; Wu, Jianlei; Li, Chuang-Chuang*, Enantioselective Total Synthesis of Cerorubenic Acid-III via Type II [5+2] Cycloaddition Reaction. J. Org. Chem. 2021, 86, (16), 11125-11139.
19. Liu, Xin#; Liu, Junyang#; Zhao, Jing; Li, Shaoping; Li, Chuang-Chuang*, Toward the Total Synthesis of Eurifoloid A. Org. Lett. 2017, 19, (10), 2742-2745.
20. Liu, Junyang; Wang, Lei; Zhang, Juefei; Xu, Zhengshuang*; Ye, Tao*, The total synthesis and stereochemical assignment of scytonemin A. Chem. Commun. 2016, 52, (5), 1002-1005.
申請及授權專利
1. 劉君羊，南慧茹，龍雄恩，邢海亮，何健飛，馬艷玲，一種環肽 Lagunamide D 的制備方法，2024-12-30，中國，2024119701774。
2. 劉君羊，龍雄恩，南慧茹，邢海亮，劉昊洋，一種四環肽中間體化合物及其制備方法和應用，2024-09-06，中國，202411250389.5。
3. 劉君羊，劉昊洋，邢海亮，王敏，一種六元環磺酰胺類化合物的制備方法，2024-07-12，中國，202410937674（公開）。
4. 劉君羊，南慧茹，龍雄恩，閆加磊，一種化合物及其合成方法與在肌動蛋白穩定劑的合成方法中的應用，2023-12-04，中國，2023116456812（公開）。
5. 劉君羊，景顯彤，陳婁曦，李闖創，虎皮楠生物堿骨架的合成方法，2022-02-11，中國，CN116621868A（公開）。
6. 劉君羊，吳建磊，范建紅，李闖創，甾體化合物的制備方法，2018-03-13，中國，ZL201810205745.X（授權）。
