
基本情況
李武,男,教授,博士生導師,海南省“515人才”、海南省“拔尖人才”。五邑大學藥學與食品工程學院食品營養與健康團隊負責人。
聯系方式
地址:廣東省江門市蓬江區迎賓大道中99號 五邑大學 藥學與食品工程學院
郵編:529020
郵箱:leewuu@163.com
電話:13637589796
工作經歷
2021年6月至今,五邑大學 藥學與食品工程學院 教授
2012.6-2021.5,海南大學食品科學與工程學院 教授/系主任/副院長 博士生導師
/教育部熱帶多糖資源利用工程研究中心副主任
/海南省食品營養與功能食品重點實驗室副主任
2016.11-2017.5,澳大利亞 CRSIO Food and Nutrition 訪問學者
2010.6-2012.6,廣東省農業科學院蠶業與農產品加工研究所 助理研究員
教育及學習經歷
2006.09-2010.03 江南大學 食品學院 食品營養與安全專業 博士
1995.09-1999.07 內蒙古大學 生命科學學院 微生物學專業 學士
主要研究方向
食品營養、農產品加工等領域:
1. 營養與動脈粥樣硬化等慢性代謝性疾病;
2. 腸道菌群與健康;
3. 天然活性產物;
4. 農產品加工。
承擔的主要科研項目
1. 國家自然科學基金項目:龍眼多糖腸道菌群代謝物基于DC途徑調節腸道免疫的作用與機制(31960481), 41萬,202001- 202312,主持;
2. 國家自然科學基金項目:基于Toll樣受體通路的干制龍眼多糖免疫調節活性增效機制研究(31360380),40萬,201401-201712,主持;
3. 廣東省重點建設學科科研能力提升項目:戈登氏菌U82 轉化鞣花酸改善非酒精性脂肪肝的作用與機制(2022ZDJS026,廣東省教育廳),50萬,202301-202512,主持;
4. 廣東省自然科學基金面上項目,阿克曼氏菌Y9轉化鞣花酸改善動脈粥樣硬化的作用與機制(2023A1515012801),10萬,202301-202512,主持;
5. 省科技創新戰略專項市縣科技創新支撐項目(江門市重大科技計劃“揭榜掛帥”項目),肉類預制菜加工與儲存關鍵技術及標準與產業化應用(2023-170),40.8萬元(總經費500萬元),202310-202609,主持;
6. 海南省自然科學基金-高層次人才項目:鞣花酸生物轉化尿石素的特征性腸道菌群與代謝機制研究(320RC511,海南省科技廳),7萬,202012-202312,主持;
7. 海口市重點科技計劃項目:潤腸通便食用調和油脂的研發及市場推廣(2020-022),80萬,202008-202208,主持;
8. 企業委托橫向項目:潤腸通便食用調和油脂研發(HD-KYH-2019043),18萬元,201909-202109,主持;
9. 企業委托橫向項目:灰樹花粗多糖的分離純化與免疫功能評價(HD-KYH-2020087),15萬元,202010-202110,主持;
發表的主要學術論文
1. Wenyan Xian, Shiying Yang, Yu Deng, Yuzhe Yang, Chunlian Chen, Wu Li* (通訊作者), Ruili Yang*. Distribution of Urolithins Metabotypes in Healthy Chinese Youth: Difference in Gut Microbiota and Predicted Metabolic Pathways. Journal of Agricultural and Food Chemistry, 2021, 69:13055?13065(封面文章,中科院大類1區,TOP期刊)
2. Huang XX, Li W*(通訊作者),You BY, Tang W, Gan TS, Feng C,Li CF, Yang, RL*. Serum Metabonomic Study on the Antidepressant-like Effects of Ellagic Acid in a Chronic Unpredictable Mild Stress-Induced Mouse Model. Journal of Agricultural and Food Chemistry, 2020, 68:9546-9556.(封面文章,中科院大類1區,TOP期刊)
3. Wu Li, Ruili Yang*, Danyang Ying, Jiawen Yu, Luz Sanguansri, Mary Ann Augustin. Analysis of polyphenols in apple pomace: A comparative study of different extraction and hydrolysis procedures, Industrial Crops and Products, 2020, 147, 112250.(中科院大類1 區,ESI高被引,TOP期刊)
4. Wang S, Chen J, Feng C, Lan H, Xu J, Yang R, Li C, Li W*(通訊作者). Effects of simulated digestion on the structural characteristics and dendritic cell activation of longan polysaccharides. International Journal of Biological Macromolecules. 2023,238:124114. (中科院大類1區,TOP期刊)
5. Wu Li, Junhong Huang, Lin Zheng, Wanshun Liu, Liqi Fan, Baoguo Sun, Guowan Su, Jucai Xu*, Mouming Zhao*, A fast stop-flow two-dimensional liquid chromatography tandem mass spectrometry and its application in food-derived protein hydrolysates. Food Chemistry, 2022,11:135000(中科院大類1區,TOP期刊)
6. Cai, K; Dou, R ; Lin, X (Lin, Xue) ; Hu, XP; Wang, ZL; Liu, SX; Li, CF ; Li, W* (通訊作者). Changes in Phenolic Profiles and Inhibition Potential of Macrophage Foam Cell Formation during Noni (Morinda citrifolia Linn.) Fruit Juice Fermentation. Fermentation-Basel, 2022,8(5):e201(中科院大類2區)
7. Haibo Lan, Wu Li*(通訊作者), Jucai Xu, Yuzhe Yang, Zhaolun Tan, Ruili Yang. A Novel Polysaccharide Isolated from Fresh Longan (Dimocarpus longan Lour.) Activates Macrophage via TLR2/4-mediated PI3/AKT and MyD88/TRAF6 Pathways. Frontiers in Pharmacology, 2021, 786127(中科院大類2區,TOP期刊)
8. You, B.Y., Yang, S.Y., Yu, J.W., Xian, W.Y., Deng, Y., Huang, W., Li, W.*(通訊作者), Yang, R.L.*. Effect of thermal and dry salt-curing processing on free and bound phenolics and antioxidant activity in Prunus mume fruits together with the phenolic bioaccessibility. LWT-Food Science and Technology. 2021, 145:111355. (中科院大類1區,TOP期刊)
9. Tingsheng Gan, Chao Feng, Haibo Lan, Ruili Yang, Jiachao Zhang, Congfa Li, Wu Li*(通訊作者). Comparison of the Structure and Immunomodulatory Activity of Polysaccharides from Fresh and Dried Longan. Journal of Functional Foods, 2021,76 : 104323 (中科院大類2區,TOP期刊)
10. Rong Yu, Yang Ruili, Yang Yuzhe, Wen Yazhou, Liu Sixin; Li Congfa; Hu Zhouyan, Cheng Xiangrong, Li Wu*(通訊作者). Structural characterization of an active polysaccharide of longan and evaluation of immunological activity. Carbohydrate Polymers, 2019, 213(6): 247-256. (中科院大類1區,TOP期刊)
11. Jiang Shuaiming, Ma Chenchen, Peng Qiannan, Huo Dongxue, Wu Li*(通訊作者), Zhang Jiachao*. Microbial profile and genetic polymorphism of predominant species in some traditional fermented seafoods of the Hainan area in China, Frontiers in Microbiology, 2019, 12: e564(中科院大類2區,TOP期刊)
12. Jiachao Zhang, Guangmei Yang, Yazhou Wen1, Sixin Liu, Congfa Li, Ruili Yang, Wu Li*(通訊作者). Intestinal microbiota are involved in the immunomodulatory activities of longan polysaccharide. Molecular Nutrition & Food Research, 2017,61(11):1700466 (中科院大類1區,TOP期刊)